Tuesday, October 12, 2010

Two people of normal health have a child with hemophilia (sex-linked recessive)


Two people of normal health have a child with hemophilia (sex-linked recessive)?
What are the genotypes of both parents? Explain
Biology - 3 Answers
 
Random Answers, Critics, Comments, Opinions :
1 :
The parents are heterozygous for hemophilia. In order for the child to have it, he/she would have to inherit 1 copy of the recessive gene from each parent, otherwise the trait would be masked by the non-hemophilia gene.
2 :
Dad has X (normal) y Mom has X (normal) X(hemophelia) The child is a boy the boy's genotype is X (hemophelia) Y
3 :
H=Hemophilia n=Normal Dad=Xn y Mom=XH Xn Unless you know that the dad is affected by the disease (in which case he probably wouldn't be having a child), the faulty gene comes entirely from the mother. Since the Hemophilia gene is recessive the mother won't have any symptoms of the disease. The problem is: 50% of this couples male children will have the disease, and 25% of their total children will have it, and 25% of the female children will be carriers.





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